Science and Therapeutics

Serum Therapy in Therapeutics and Medical Science

Serum therapy in the form in which it finds application in the treatment of diphtheria patients is an antitoxic or detoxicating curative method. It is based on the view, held by Löffler in Germany and by Roux in France, that the parasites causing diphtheria, the Löffler diphtheria bacilli, do not themselves cause diphtheria, but that they produce poisons which cause the disease to develop. With...

Art, Science, and Personalized Cancer Care Through Regional Therapeutics.

Application of microbial genomic science to advanced therapeutics.

Since the publication of the first complete microbial genome sequence of Haemophilus influenzae in 1995, more than 200 additional microbial genome sequences have become available in the public domain. Approximately 40% of these represent important human pathogens. Comparative in silico methods, along with large-scale approaches such as transcriptomics and proteomics, are beginning to reveal ins...

An Overview of Biologics: Science behind Protein Therapeutics

Biosimilars or ‘follow-on biologics’ are new biopharmaceutical agents that are ‘similar’ but not identical to a reference biopharmaceutical product. Biosimilars are considered ‘comparable’ to the reference product, but this does not ensure therapeutic equivalence. Inherent differences between biosimilars may produce dissimilarities in clinical efficacy, safety, and immunogenicity. Therefore acc...

Rational design and engineering of delivery systems for therapeutics: biomedical exercises in colloid and surface science.

Engineering delivery systems of therapeutic agents has grown into an independent field, transcending the scope of traditional disciplines and capturing the interest of both academic and industrial research. At the same time, the acceleration in the discovery of new therapeutic moieties (chemical, biological, genetic and radiological) has led to an increasing demand for delivery systems capable ...